SEM4C Rabbit Polyclonal Antibody

Description: SEM4C Rabbit Polyclonal Antibody

Description: SEM4C Rabbit Polyclonal Antibody

Description: Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins| semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities| semaphorins are put into eight classes: invertebrates contain classes 1 and 2| viruses have class V| and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes| some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

Description: Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins| semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities| semaphorins are put into eight classes: invertebrates contain classes 1 and 2| viruses have class V| and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes| some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

Description: Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins| semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities| semaphorins are put into eight classes: invertebrates contain classes 1 and 2| viruses have class V| and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes| some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

Description: The transcription of this gene is activated by PPAR-gamma| and the resulting protein product plays a role in endothelial cell migration. Expression of this gene also inhibits tumor cell migration and invasion.

Description: The transcription of this gene is activated by PPAR-gamma| and the resulting protein product plays a role in endothelial cell migration. Expression of this gene also inhibits tumor cell migration and invasion.

Description: The transcription of this gene is activated by PPAR-gamma| and the resulting protein product plays a role in endothelial cell migration. Expression of this gene also inhibits tumor cell migration and invasion.

Description: This gene encodes a transmembrane class IV semaphorin family protein| which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer| the development of neurofibromas| and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants.

Description: This gene encodes a transmembrane class IV semaphorin family protein| which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer| the development of neurofibromas| and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants.

Description: This gene encodes a transmembrane class IV semaphorin family protein| which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer| the development of neurofibromas| and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants.