Endothelial cell dysfunction is a outstanding function of diabetic cardiovascular issues, and endothelial cell senescence is taken into account to be an vital contributor to endothelial dysfunction. Discoidin area receptor 1 (DDR1) has been reported to be concerned in atherogenesis and cerebral ischemia/reperfusion damage. In this examine, we aimed to discover the function of DDR1 in endothelial cell senescence underneath diabetic situations and elucidate the underlying mechanisms.
A diabetic rat mannequin was established by a single intraperitoneal injection of streptozocin (STZ) (60 mg/kg), which confirmed a rise in senescence-associated β-galactosidase (SA-β-gal) staining sign of thoracic aortic endothelium, impaired vascular construction and performance, accompanied by an up-regulation of DDR1. Next, we verified the function of DDR1 in endothelial senescence and the underlying mechanisms in excessive glucose-treated human umbilical vein endothelial cells (HUVECs).
Consistent with the in vivo findings, excessive glucose induced endothelial senescence, impaired endothelial operate and elevated DDR1 expression, accompanied by the elevation of senescence-related genes p53 and p21 expression, and these results have been reversed by DDR1 siRNA. DDR1 has been documented to be a possible goal of miR-199a-3p.
Here, we discovered that miR-199a-3p was down-regulated by excessive glucose in the aorta tissue and HUVECs, whereas miR-199a-3p mimic considerably suppressed elevated endothelial senescence and elevated DDR1 induced by excessive glucose.
In conclusion, our information demonstrated that miR-199a-3p/DDR1/p53/p21 signaling pathway was concerned in endothelial senescence underneath diabetic situations, and therapeutic concentrating on DDR1 could be exploited to inhibit endothelial senescence owing to excessive glucose publicity.
Study of blood glucose and insulin infusion charge in real-time in diabetic rats utilizing a synthetic pancreas system
Artificial pancreas system (APS) is an rising new therapy for kind 1 diabetes mellitus. The intention of this examine was to develop a rat APS as a analysis software and show its software. We established a rat APS utilizing Medtronic Minimed Pump 722, Medtronic Enlite sensor, and the open synthetic pancreas system as a controller.
We examined totally different dilutions of Humalog (100 items/ml) in saline ranged from 1:Three to 1:20 and decided that 1:7 dilution works effectively for rats with ~500g body weight. Blood glucose ranges (BGL) of diabetic rats fed with chow food plan (58% carbohydrate) whose BGL was managed by the closed-loop APS for the overall period of 207h have been in euglycemic vary (70-180 mg/dl) for 94.5% of the time with 2.1% and three.4% for hyperglycemia (>180mg/dl) and hypoglycemia (<70 mg/dl), respectively.
Diabetic rats fed with Sucrose pellets (94.8% carbohydrate) for the experimental period of 175h have been in euglycemic vary for 61% of the time with 35% and 4% for hyperglycemia and hypoglycemia, respectively. Heathy rats fed with chow food plan confirmed nearly a straight line of BGL ~ 95 mg/dl (common 94.Eight mg/dl) throughout the complete experimental interval (281h), which was minimally altered by meals consumption.
In the wholesome rats, feeding sucrose pellets induced larger vary of BGL in excessive and low ranges however nonetheless inside euglycemic vary (99.9%). Next, to check how wholesome and diabetic rats deal with supra-physiological concentrations of glucose, we intraperitoneally injected varied quantities of 50% dextrose (2, 3, 4g/kg) and monitored BGL.

Duration of hyperglycemia after injection of 50% dextrose in any respect three totally different concentrations was considerably larger for wholesome rats than diabetic rats, suggesting that insulin infusion by APS was superior in decreasing BGL as in comparison with pure insulin launched from pancreatic β-cells. Ex vivo research confirmed that islets remoted from diabetic rats have been nearly fully devoid of pancreatic β-cells however with intact α-cells as anticipated.
Lipid droplet deposition in the liver of diabetic rats was considerably decrease with greater ranges of triacylglyceride in the blood as in comparison with these of wholesome rats, suggesting lipid metabolism was altered in diabetic rats. However, glycogen storage in the liver decided by Periodic acid-Schiff staining was not altered in diabetic rats as in comparison with wholesome rats.
A rat APS could also be used as a strong software not solely to check alterations of glucose and insulin homeostasis in real-time attributable to food plan, train, hormones, or antidiabetic brokers, but in addition to check mathematical and engineering fashions of blood glucose prediction or new algorithms for closed-loop APS.
A evaluate on community pharmacology based mostly phytotherapy in treating diabetes– An environmental perspective
Diabetes has grow to be frequent life-style dysfunction related to weight problems and cardiovascular ailments. Environmental components like bodily inactivity, polluted environment and unhealthy weight-reduction plan additionally performs an important function in diabetes pathogenesis.
As the present anti-diabetic medicine possess unprecedented unintended effects, conventional natural drugs can be utilized another remedy. The paramount problem with the natural formulation utilization is the dearth of standardized process, entangled with little data on drug security and mechanism of drug motion. Heavy metallic contamination is a significant environmental hazard the place crops are likely to accumulate poisonous metals like nickel, chromium and lead by industrial and agricultural actions.
It turns into inappropriate to make use of these crops for phytotherapy as it could have an effect on the human well being on long run consumption. This evaluate focus on concerning the environmental threat components associated to diabetes and higher implication of medicinal crops in anti-diabetic remedy utilizing community pharmacology. It is an in silico analytical software that helps to unravel the multi-targeted motion of natural formulations wealthy in secondary metabolites.
ExoStd? Lyophilized Exosome Standard (30 µg, U87 MG, 2 vials) |
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M1054-2 | Biovision | each | 724.8 EUR |
ExoStd? Lyophilized Exosome Standard (100 µg, U87 MG, 2 vials) |
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M1055-2 | Biovision | each | 861.6 EUR |
ExoStd? Lyophilized Exosome Standard (30 µg, COLO1 cell line, 2 vials) |
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M1048-2 | Biovision | each | 724.8 EUR |
ExoStd? Lyophilized Exosome Standard (100 µg, COLO1 cell line, 2 vials) |
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M1049-2 | Biovision | each | 861.6 EUR |
ExoStd? Lyophilized Exosome Standard (30 µg, MM1 cell line, 2 vials) |
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M1050-2 | Biovision | each | 724.8 EUR |
ExoStd? Lyophilized Exosome Standard (100 µg, MM1 cell line, 2 vials) |
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M1051-2 | Biovision | each | 861.6 EUR |
ExoStd? Lyophilized Exosome Standard (30 µg, BLCL21 cell line, 2 vials) |
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M1052-2 | Biovision | each | 724.8 EUR |
ExoStd? Lyophilized Exosome Standard (100 µg, BLCL21 cell line, 2 vials) |
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M1053-2 | Biovision | each | 861.6 EUR |
ExoStd? Lyophilized Exosome Standard (30 µg, HCT116 cell line, 2 vials) |
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M1058-2 | Biovision | each | 724.8 EUR |
ExoStd? Lyophilized Exosome Standard (100 µg, HCT116 cell line, 2 vials) |
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M1059-2 | Biovision | each | 861.6 EUR |
ExoStd? Lyophilized Exosome Standard (30 µg, PC3 cell line, 2 vials) |
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M1060-2 | Biovision | each | 724.8 EUR |
ExoStd? Lyophilized Exosome Standard (100 µg, PC3 cell line, 2 vials) |
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M1061-2 | Biovision | each | 861.6 EUR |
ExoStd? Lyophilized Exosome Standard (30 µg, DAUD1 cell line, 2 vials) |
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M1064-2 | Biovision | each | 724.8 EUR |
ExoStd? Lyophilized Exosome Standard (100 µg, DAUD1 cell line, 2 vials) |
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M1065-2 | Biovision | each | 861.6 EUR |
ExoStd? Lyophilized Exosome Standard (30 µg, A549 cell line, 2 vials) |
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M1066-2 | Biovision | each | 724.8 EUR |
ExoStd? Lyophilized Exosome Standard (100 µg, A549 cell line, 2 vials) |
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M1067-2 | Biovision | each | 861.6 EUR |
ExoStd? Lyophilized Exosome Standard (30 µg, B16F10 cell line, 2 vials) |
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M1070-2 | Biovision | each | 724.8 EUR |
ExoStd? Lyophilized Exosome Standard (100 µg, B16F10 cell line, 2 vials) |
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M1071-2 | Biovision | each | 861.6 EUR |
ExoStd? Lyophilized Exosome Standard (30 µg, BPH-1 cell line, 2 vials) |
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M1062-2 | Biovision | each | 724.8 EUR |
ExoStd? Lyophilized Exosome Standard (100 µg, BPH-1 cell line, 2 vials) |
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M1063-2 | Biovision | each | 861.6 EUR |
ExoStd? Lyophilized Exosome Standard (30 µg, K-562 cell line, 2 vials) |
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M1068-2 | Biovision | each | 724.8 EUR |
ExoStd? Lyophilized Exosome Standard (100 µg, K-562 cell line, 2 vials) |
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M1069-2 | Biovision | each | 861.6 EUR |
ExoStd? Lyophilized Exosome Standard (30 µg, SK-N-SH cell line, 2 vials) |
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M1056-2 | Biovision | each | 724.8 EUR |
ExoStd? Lyophilized Exosome Standard (100 µg, SK-N-SH cell line, 2 vials) |
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M1057-2 | Biovision | each | 861.6 EUR |
SARS-CoV-2 Nucleocapsid Protein, Avi-His-tag |
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E80027 | EpiGentek |
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Recombinant SARS-CoV-2 Spike Glycoprotein(S) (D614G), Partial |
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E80028 | EpiGentek |
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SARS-CoV-2 Spike S1 RBD Protein, Avi-His-tag |
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E80024 | EpiGentek |
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SARS-CoV-2 Spike S1 RBD Protein, Mouse Fc-fusion |
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E80026 | EpiGentek |
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SARS-CoV-2 Spike S1 (16-685) Protein, Avi-His-tag |
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E80021 | EpiGentek |
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SARS-CoV-2 Spike S1 RBD (V367F) Protein, Avi-His-tag |
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E80023 | EpiGentek |
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SARS-CoV-2 Spike S1 (13-665) Protein, Fc Fusion, Avi-tag |
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E80020 | EpiGentek |
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SARS-CoV-2 Spike S1 (16-685) Protein, Fc Fusion, Avi-tag |
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E80022 | EpiGentek |
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SARS-CoV-2 Spike S1 RBD Protein, Human Fc-Fusion, Avi-Tag |
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E80025 | EpiGentek |
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Exosome Component 2 (EXOSC2) Antibody |
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20-abx172308 | Abbexa |
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Exosome Component 2 (EXOSC2) Antibody |
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20-abx125830 | Abbexa |
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Exosome Component 2 (EXOSC2) Antibody |
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20-abx112411 | Abbexa |
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Exosome Component 2 (EXOSC2) Antibody |
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20-abx003412 | Abbexa |
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Exosome Component 2 (EXOSC2) Antibody |
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abx034983-400ul | Abbexa | 400 ul | 627.6 EUR |
Exosome Component 2 (EXOSC2) Antibody |
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abx034983-80l | Abbexa | 80 µl | 343.2 EUR |
Exosome Component 2 (EXOSC2) Antibody |
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abx232901-100ug | Abbexa | 100 ug | 577.2 EUR |
Exosome Component 2 (EXOSC2) Antibody |
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abx232902-100ug | Abbexa | 100 ug | 661.2 EUR |
Exosome Component 2 (EXOSC2) Antibody |
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20-abx176346 | Abbexa |
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Recombinant Transmembrane Protease Serine 2 Protein, Partial |
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E80016 | EpiGentek |
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TNFR2 Tumor Necrosis Factor Receptor Type 2 Human Recombinant Protein |
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PROTP20333-2 | BosterBio | Regular: 20ug | 380.4 EUR |
Description: TNFR2 Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 184 amino acids and having a molecular mass of 20kDa. The TNFR2 is purified by proprietary chromatographic techniques. |
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Human Exosome Component 2 (EXOSC2) Protein |
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20-abx653328 | Abbexa |
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Human Exosome Component 2 (EXOSC2) ELISA Kit |
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DLR-EXOSC2-Hu-48T | DL Develop | 48T | 620.4 EUR |
Description: A sandwich quantitative ELISA assay kit for detection of Human Exosome Component 2 (EXOSC2) in samples from tissue homogenates, cell lysates or other biological fluids. |
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Human Exosome Component 2 (EXOSC2) ELISA Kit |
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DLR-EXOSC2-Hu-96T | DL Develop | 96T | 807.6 EUR |
Description: A sandwich quantitative ELISA assay kit for detection of Human Exosome Component 2 (EXOSC2) in samples from tissue homogenates, cell lysates or other biological fluids. |
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Human Exosome Component 2 (EXOSC2)ELISA Kit |
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201-12-2689 | SunredBio | 96 tests | 528 EUR |
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
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Human Exosome Component 2 (EXOSC2) ELISA Kit |
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20-abx151457 | Abbexa |
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Human Exosome Component 2 (EXOSC2) CLIA Kit |
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20-abx495555 | Abbexa |
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Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human) |
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4-PAH822Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2) |
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Human Exosome Component 2(EXOSC2)ELISA Kit |
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QY-E01130 | Qayee Biotechnology | 96T | 433.2 EUR |
Human Exosome Component 2 (EXOSC2) ELISA Kit |
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RD-EXOSC2-Hu-48Tests | Reddot Biotech | 48 Tests | 625.2 EUR |
Human Exosome Component 2 (EXOSC2) ELISA Kit |
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RD-EXOSC2-Hu-96Tests | Reddot Biotech | 96 Tests | 867.6 EUR |
Human Exosome Component 2 (EXOSC2) ELISA Kit |
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RDR-EXOSC2-Hu-48Tests | Reddot Biotech | 48 Tests | 652.8 EUR |
Human Exosome Component 2 (EXOSC2) ELISA Kit |
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RDR-EXOSC2-Hu-96Tests | Reddot Biotech | 96 Tests | 907.2 EUR |
Human Exosome Component 2 (EXOSC2) ELISA Kit |
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SEH822Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | 5677.8 EUR |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 2 (EXOSC2) in Tissue homogenates, cell lysates and other biological fluids. |
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Human Exosome Component 2 (EXOSC2) ELISA Kit |
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SEH822Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | 572.76 EUR |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 2 (EXOSC2) in Tissue homogenates, cell lysates and other biological fluids. |
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Human Exosome Component 2 (EXOSC2) ELISA Kit |
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SEH822Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | 766.8 EUR |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 2 (EXOSC2) in Tissue homogenates, cell lysates and other biological fluids. |
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Human Exosome Component 2 (EXOSC2) ELISA Kit |
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SEH822Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | 3090.6 EUR |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 2 (EXOSC2) in Tissue homogenates, cell lysates and other biological fluids. |
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Human Exosome Component 2 (EXOSC2) ELISA Kit |
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4-SEH822Hu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Exosome Component 2 (EXOSC2) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
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Human Exosome Component 2 ELISA Kit (EXOSC2) |
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RK01330 | Abclonal | 96 Tests | 625.2 EUR |
Human Exosome Component 2 (EXOSC2)ELISA Kit |
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YLA3329HU-48T | Shanghai YL Biotech | 48T | 435 EUR |
Human Exosome Component 2 (EXOSC2)ELISA Kit |
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YLA3329HU-96T | Shanghai YL Biotech | 96T | 562.5 EUR |
Lyophilized Exosome Standards |
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ExoA375 | ImmunoStep | 100 μg | 364.2 EUR |
Lyophilized Exosome Standards |
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ExoHT29 | ImmunoStep | 100 μg | 364.2 EUR |
Lyophilized Exosome Standards |
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ExoMCF7 | ImmunoStep | 100 μg | 364.2 EUR |
Lyophilized Exosome Standards |
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ExoPC3 | ImmunoStep | 100 μg | 364.2 EUR |
Lyophilized Exosome Standards |
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ExoPLASMA | ImmunoStep | 100 μg | 364.2 EUR |
Lyophilized Exosome Standards |
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ExoUrine | ImmunoStep | 100 μg | 364.2 EUR |
Exosome precipitation Solution |
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EPStep | ImmunoStep | 12 ml | 333 EUR |
ACE2, His-Tag Protein |
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E80019 | EpiGentek |
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2-Methoxyestradiol (2-MeOE2) |
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27762-2 | BPS Bioscience | 100 mg | 230 EUR |
Description: 2-Methoxyestradiol (2-MeOE2), an endogenous metabolite of 17β-estradiol (E2), is an inhibitor of microtubule assembly that inhibits the polymerization of tubulin and interferes with mitotic spindle dynamics leading to the blockage of mitosis of human cancer cells which lack estrogen receptors in metaphase. 2-MeOE2 is also an inhibitor of tumor growth and angiogenesis. Study results have shown that 2-MeOE2 induces mammalian cell transformation and genotoxicity in Syrian hamster embryo (SHE) fibroblasts through concentration-dependent inhibition of cell growth. Moreover, 2-MeOE2 has demonstrated anti-proliferative activity against estrogen-responsive breast cancer cell line MCF-7 and subsequent inhibition of the growth of tumors subcutaneously inoculated in mice. |
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ELISA kit for Human EXOSC2 (Exosome Component 2) |
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ELK4639 | ELK Biotech | 1 plate of 96 wells | 518.4 EUR |
Description: A sandwich ELISA kit for detection of Exosome Component 2 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
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Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), APC |
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4-PAH822Hu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with APC. |
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Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), Biotinylated |
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4-PAH822Hu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with Biotin. |
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Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), Cy3 |
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4-PAH822Hu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with Cy3. |
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Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), FITC |
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4-PAH822Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with FITC. |
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Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), HRP |
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4-PAH822Hu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with HRP. |
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Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), PE |
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4-PAH822Hu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with PE. |
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XStamp IL2 exosome IL-2 receptor targeting lentivector |
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XSTP726PA-1 | SBI | 10 ug | 991.2 EUR |
FluoroCet Exosome Quantitation Kit |
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FCET96A-1 | SBI | 96 reactions | 871.2 EUR |
Fluorescent Exosome Standard (Urine ) |
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ESF-15 | Creative Biolabs | 100 µg | 2067.6 EUR |
Description: Fluorescent exosomes are labeled with green dye, which offer a stable fluorescent labeling. |
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EXOCET Exosome Quantitation Kit |
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EXOCET96A-1 | SBI | 96 reactions | 625.2 EUR |
Exosome Component 9 Peptide |
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46-967P | ProSci | 0.1 mg | 405.6 EUR |
Description: (CT) PMSCL1 Peptide |
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Exosome Component 5 Protein |
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20-abx260873 | Abbexa |
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Exosome Component 7 Protein |
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20-abx261347 | Abbexa |
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Exosome Component 10 Protein |
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20-abx261805 | Abbexa |
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Exosome Component 4 Protein |
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20-abx261954 | Abbexa |
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Exosome Component 9 Protein |
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20-abx262123 | Abbexa |
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Exosome Component 8 Protein |
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20-abx262850 | Abbexa |
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Exosome Component 3 Protein |
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20-abx263422 | Abbexa |
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Exosome Component 1 Protein |
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20-abx263423 | Abbexa |
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Nori® Human Angiopoietin-2 (ANG-2) ELISA Kit (2 plates) |
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GR106245-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Nori Equine MMP-2/TIMP-2 Complex ELISA Kit (2 plates) |
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GR106502-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
2-Propyl-β-D-glucuronide, 2 mg |
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0904-2 | AthenaES | 2 mg | 194.4 EUR |
BNP Human, B-type Natriuretic Peptide Human Recombinant Protein, His Tag |
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PROTP16860-2 | BosterBio | Regular: 10ug | 380.4 EUR |
Description: BNP Recombinant Human fused with 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 129 amino acids (27-134 a.a) and having a molecular mass of 14 kDa.   |
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Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), APC-Cy7 |
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4-PAH822Hu01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with APC-Cy7. |
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Nori® Human MMP-2/TIMP-2 Complex ELISA Kit (2 plates) |
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GR106372-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Nori® Human b-defensin 2 (BD-2) ELISA Kit- 2 Plates |
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GR111099-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Nori Equine MMP-2 ELISA Kit-2 Plates |
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GR106478-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Nori Equine TIM-2 ELISA Kit (2 plates) |
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GR106516-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Nori Human TIM-2 ELISA Kit-2 Plates |
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GR111039-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Nori Canine TIM-2 ELISA Kit (2 plates) |
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GR115041-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Monoclonal Anti-Dengue Virus Type 1-4 (pan, NS1) IgG, clone 2 (pairs with clone 1) |
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AB-21122-2 | Alpha Diagnostics | 0.5 ml | 634.8 EUR |
2 M NaCl |
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GR103063-2 | Genorise Scientific | 200 mL | 70.8 EUR |
Thaw Medium 2 |
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60184-2 | BPS Bioscience | 500 ml | 675 EUR |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including_x000D__x000D_• PD-1/NFAT Reporter-Jurkat cell #60535_x000D__x000D_• NFAT Reporter (Luc) - Jurkat Cell Line #60621_x000D__x000D_• NF-ĸB-Luciferase Reporter (Luc) - Jurkat Cell Line #60651_x000D__x000D_• ADCC Bioassay Effector Cell F variant (Low Affinity) #60540_x000D__x000D_• ADCC Bioassay Effector Cell V variant (High Affinity) #60541_x000D__x000D_Note: once cells are well-established, switch to the appropriate cell growth medium. |
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Apoptosis Activator 2 |
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27733-2 | BPS Bioscience | 50 mg | 390 EUR |
Description: Apoptosis Activator 2 is a small, cell permeable activator of caspase-3. Apoptosis Activator 2 induces apoptosis specifically in tumor cell lines, but not normal cell lines, with IC50 value of about 4 µM. |
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Recombinant TMPRSS2 Protein, Partial |
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E80017 | EpiGentek |
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Recombinant Novel Coronavirus Spike Glycoprotein(S), Partial |
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E80018 | EpiGentek |
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HPV type 2 |
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DAG4703 | Creative Diagnostics | 0.25 mg | 864 EUR |
HPV type 2 |
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DAG206 | Creative Diagnostics | 1 ml | 1057.2 EUR |
Nori® Chicken Netrin-2 ELISA Kit (2 plates) |
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GR106184-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Nori® Human Tie-2 ELISA Kit (2 plates) |
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GR106458-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Nori® Human TIMP-2 ELISA Kit (2 plates) |
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GR106460-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Nori® Human Trappin-2 ELISA Kit (2 plates) |
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GR106467-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Nori® Rabbit IL-2 ELISA Kit- 2 Plates |
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GR144032-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Nori® Monkey IL-2 ELISA Kit- 2 Plates |
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GR169004-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Nori® Donkey IL-2 ELISA Kit- 2 Plates |
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GR170004-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Nori® Porcine MMP-2 ELISA Kit- 2 Plates |
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GR113006-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Nori® Chicken MMP-2 ELISA Kit- 2 Plates |
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GR114008-2 | Genorise Scientific | 2 x 96-well | 998.4 EUR |
Also, a particular focus is tried to pool the databases concerning the medicinal crops for diabetes and related ailments, their bioactive compounds, attainable diabetic targets, drug-target interplay and toxicology experiences which will open an aisle in safer, efficient and toxicity-free drug discovery.